Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation

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Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation

PURPOSE Here, we investigated the formation and functional properties of self-assembled lecithin/chitosan nanoparticles (L/C NPs) loaded with insulin following insulin-phospholipid complex preparation, with the aim of developing a method for oral insulin delivery. METHODS Using a modified solvent-injection method, insulin-loaded L/C NPs were obtained by combining insulin-phospholipid complexe...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2016

ISSN: 1178-2013

DOI: 10.2147/ijn.s96146